Trizyc Health
Cognitive Performance Score

Measure Your Cognitive Performance

Calculate your Cognitive Performance Score (CPS) by combining biomarker analysis, self-reported cognitive function, and lifestyle behaviors. Understand the factors affecting your brain health and identify areas for improvement.

Chronic Stress Load (45%)

Evaluates your physiological stress burden through metabolic, inflammatory, and cardiovascular biomarkers using the allostatic load methodology.

Cognitive Function (25%)

Uses the PROMIS Cognitive Function 4a questionnaire to assess your self-reported mental sharpness, memory, thinking speed, and task tracking.

Lifestyle Behaviors (30%)

Assesses sleep quality, physical activity patterns, and mental recovery practices that directly impact cognitive performance.

About the CPS Algorithm

How is CPS Calculated?

The Cognitive Performance Score combines three key components using a weighted formula.

Lower chronic stress load and higher cognitive/behavior scores result in a higher CPS, indicating better cognitive performance potential.

Interpreting Your Score

80-100: Strong cognitive clarity baseline
60-79: Generally good; target optimizations
40-59: Meaningful strain; improvement plan recommended
0-39: High concern zone

Trizyc Cognitive Performance Score (CPS) is a proprietary composite designed for working-age adults to quantify day-to-day “mental clarity” (sharpness, speed of thinking, working memory/attention) by integrating PROMIS Adult Cognitive Function 4a, biologic stress physiology, and behavioral recovery factors. PROMIS 4a provides a robust, U.S. population-validated foundation, while integrating behavioral data with physiologic stress and recovery signals enables a more well-rounded assessment of an individual’s attention, working memory, and executive decision-making.


Iverson, G. L., et al. (2021). "Normative Reference Values, Reliability, and Item-Level Symptom Endorsement for the PROMIS® v2.0 Cognitive Function-Short Forms 4a, 6a and 8a." Archives of Clinical Neuropsychology, 36(7), 1341–1349.
Saffer, B. Y., et al. (2015). "Assessing cognitive impairment using PROMIS® applied cognition-abilities scales in a medical outpatient sample." Psychiatry Research, 226(1), 199–205.
Echouffo-Tcheugui, J. B., et al. (2018). "Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study." Neurology, 91(21), e1961–e1970.
Shields, G. S., Bonner, J. C., & Moons, W. G. (2015). "Does cortisol influence core executive functions? A meta-analysis of acute cortisol administration effects on working memory, inhibition, and set-shifting." Psychoneuroendocrinology, 58, 91–103.
Lim, J., & Dinges, D. F. (2010). "A Meta-Analysis of the Impact of Short-Term Sleep Deprivation on Cognitive Variables." Psychological Bulletin, 136(3), 375–389.
Sartori, A. C., et al. (2012). "The impact of inflammation on cognitive function in older adults: implications for healthcare practice and research." Journal of Neuroscience Nursing, 44(4), 206–217.


For research and educational purposes only.